It sounds like the upcoming PC version of Destiny 2 will not play nice with a whole lot of popular PC software and application that PC gamers like to use. In an attempt to curtail cheating on the PC version of the title, Bungie have apparently disabled third party applications from inserting any code into the PC version of Destiny 2.
This means that popular PC apps, such as the voice chat solution Discord, streaming and capture applications like OBS, FRAPS, Razer Cortex, and GameSplit, and overlays such as MSI Afterburner, will not be supported by the game, and will variously suffer from compatibility issues (in the case of something like Discord, you may still be able to engage in voice chat; however, you will experience problems with notifications).
Considering the popularity of a lot of these applications – Discord is the preferred socializing application for PC gaming, MSI Afterburner is often used for framerate tests, and video capture is indeed integral to the large PC streaming community – this is unlikely to go down well with a lot of PC gamers. We’ll see how they react when Destiny 2 launches on PC in October, a month after the Xbox One and PS4 release.