15 Best Sandbox Missions of All Time

Situs Inversus – Hitman (2016)

As the final mission in Hitman (2016), Situs Inversus sees Agent 47 traveling to a high-tech GAMA hospital in Hokkaido, Japan to take down Erich Soders and Yuki Yamazaki. The title is renowned for returning to a more sandbox-heavy style of gameplay and Situs Inversus is perhaps the best example. Along with the usual challenges that add concealed weapons, unique starting locations and disguises, there are multiple Opportunities for eliminating your targets. Masquerade as Yamazaki’s personal trainer or serve her the more poisonous parts of fugu fish. Sabotage Soders’ donor heart or access the hospital’s mainframe and kill him with the surgery robot. The choice is yours.