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Zeke – inFamous 2
If you go the evil karma route in inFamous 2, choosing to wipe out all humans and become the leader of a new world full of Conduits, then Cole will have to battle his friends. That includes Zeke, who’s been with Cole since the first game and always had his back. Zeke is holding the RFI and pretty much stopping Cole from achieving his goal, leaving no choice but to kill him (because he’s trying to kill Cole, of course). It’s not without some regret though especially given how much effort Zeke made to redeem himself.
