Fallout 3
Bethesda doesn’t muck about when showcasing the full destructive ability of a nuke in Fallout 3. A side quest early on lets you nuke Megaton and watch the explosion from a distance. It’s a searing sight, one of the more iconic moments in the series and a reminder of how messed up the world has become. Otherwise, smaller nukes can be used as ammo for the Fat Man or Experimental MIRV, the latter delivering eight mini-nukes to be the most ridiculously overpowered shotgun ever.
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