15 Most Difficult Games of 2022

The Callisto Protocol

From the beginning in Black Iron prison, your only chance of survival against numerous Biophages is a melee weapon. Ammo is limited, and failure to kill foes before they mutate makes things even tougher. It also doesn’t help when enemies swarm and attack you off-screen. Things get easier as you unlock more weapons, and most regular Biophages can die quickly if you know what to do. But falter for even a second, and a world of pain awaits.