Isabela – Dragon Age 2
Like Zevran in the original Dragon Age, Isabela endears herself to the player only to turn around and stab them in the back. What makes this so much worse is that she is also a possible romantic interest in the game. So you can spend most of the game trying to win her heart, only for her to break it in the end. Adding insult to injury, she returns and tries to apologize and make amends.
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