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DESTROY ALL HUMANS!
Another obvious pick- because if you’re looking for a game where messing with the NPCs is the whole point, you can’t really go wrong with Destroy All Humans! Crypto has a wide and varied arsenal of alien weapons and tools as well as his own psychokinetic abilities that he can use to wreak havoc in a multitude of ways. And if that isn’t enough, he can always just jump into his flying saucer and deal destruction of an even wider scale. And somehow, that never gets boring.
