15 Most Powerful Weapons In Resident Evil

COLT ANACONDA – (RESIDENT EVIL REMAKE)

Barry Burton’s love for his weapons is well-known to all Resident Evil fans, and he loves no weapons as much as he loves his magnum. He famously had a buddy system going on with his 44 magnum, the Colt Anaconda, in the RE1 remake, and when you use the weapon for yourself, it’s easy to see why he loves it so much. Hell, it can take out the Tyrant’s first form in a single shot. Unfortunately, you can only use the weapon if Barry dies, so it might not be a fair trade-off…