Tony Todd, who is playing Venom in the upcoming Marvel's Spider-Man 2, says Insomniac's superhero sequel is going to be "massive."
The journey of both Peter and Miles will continue. Bryan Intihar and Ryan Smith also return as creative director and game director respectively.
Miles Morales and Peter Parker team up to battle a mysterious new foe. Meanwhile, somewhere in the darkness, Venom also awaits.
Nadji Jeter, who portrays Miles Morales, recently uploaded (and deleted) a photo of himself in motion capture gear, fueling speculation that Marvel's Spider-Man 2 is in the works.
Marvel Games' Bill Rosemann says the plan is to "keep each game set in its own universe."
The Last of Us Part 2 ranks at fourth despite being released only last month.