Nemesis – Resident Evil 3
This guy has one ugly mug. Don't tell him I said that though. His vein-heavy skin and gnarling teeth are pretty intimidating, not to mention that the guy is f***ing stacked and purpose-built for destruction. And, as it sort of counts as the face area, we can't neglect the fact that he has a rocket launcher attached to his shoulder. Discretion would be the better part of valour in this particular encounter.
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