14 Most Difficult Boss Fights of 2021 So Far

Hemovorous and Vermivorous the Invincible – Borderlands 3: Director’s Cut

As the final raid boss added to the game, Hemovorous the Invincible can be a doozy even without any Mayhem modifiers. It has tons of health, deals tremendous damage, constantly spawns Varkid Larva (that can become Badasses if you’re not careful) and is generally a bad time. But when playing in either Mayhem or True Vault Hunter Mode, you’ll have to deal with Vermivorous the Invincible as well who has the same amount of health. This is on top of potentially hazardous modifiers from Mayhem like increased damage or immunity to elemental damage for enemies.