Dishonored 2
Of course, Arkane’s crowning glory in the immersive sim genre is Dishonored with Dishonored 2 easily being the best. You start with either Emily or Corvo, each having unique abilities, and can tackle missions through stealth, assassinations or pure violence. Environments are fairly sand-boxy, presenting several different choices, like killing foes all at once with powers like Domino or manipulating plague rats, along with side quests, puzzles and Relics. Depending on how brutal you were, the ending can change significantly so some caution is advised but that just fuels the creativity even more.
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